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What is Endocannabinoid System?

In this blog, we’re explaining what is the endocannabinoid system and its role in the body.

Table of Contents

  1. Endocannabinoid System
  2. Role of Endocannabinoid System
  3. How Endocannabinoid System Work
  4. Conclusion


Endocannabinoid System

The Endocannabinoid system, in short, ECS, which plays a vital role in your body. This system contains three essential things. It includes endocannabinoids, receptors all over the body and nervous system, and enzymes.

According to the research, the ECS plays a crucial role in various body functions.

Role of the Endocannabinoid System

As we mentioned above, this system has a crucial role in several body functions.

This includes:

  • Appetite
  • Sleep
  • Reproduction
  • Mood
  • Memory
  • Metabolism
  • Cardiovascular system function
  • Inflammation
  • Stress
  • Functioning of liver
  • The functioning of nerve and skin
  • And a lot more.

Next, let’s have a look into its functioning process.

How does the Endocannabinoid System work?

The ECS works with the help of its three components that we mentioned in the starting. They are endocannabinoids, enzymes, and receptors.

Let’s have a detailed view of it.


This is also popular as endogenous cannabinoids. Basically, these are the molecules produced by the body.

As per the scientists, the two key endocannabinoids are anandamide (AEA) and 2-arachidonoylglyerol (2-AG). These endocannabinoids help the internal body functions to run smoothly.

Endocannabinoid Receptors

These are present all over the body. When it comes to receptors, there are two main are CB1 and CB2.

CB1 receptors mainly exist in your central nervous system.

CB2 receptors exist in the peripheral nervous system, mainly immune cells.

Endocannabinoids can interact with these receptors and the interaction can be beneficial for health.

For example, if these cannabinoids bind with the CB1 in the spinal nerve, then it results in alleviating pain.


This component is liable for breaking down cannabinoids. The two important enzymes present in the ECS are monoacylglycerol acid lipase and fatty acid amide hydrolase. The fatty acid amide hydrolase breaks down anandamide, and monoacylglycerol acid lipase breaks down 2-arachidonoylglyerol.


The ECS is responsible for keeping your internal functions stable. In fact, this system plays a significant role in this.

We hope that this blog has served to make you clear almost everything about ECS and its functions.

Endocannabinoid System